Ser339
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Home > Phosphorylation Site Page: > Ser339  -  CDC37 (human)

Site Information
HMQRCIDsGLWVPNs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 62877802

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
colorectal cancer ( 1 ) , colorectal carcinoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
ULK1 (human) ( 1 )
Kinases, in vitro:
ULK1 (human) ( 1 )

Downstream Regulation
Effects of modification on CDC37:
molecular association, regulation ( 1 )
Inhibit interaction with:
AurB (human) ( 1 ) , CDK4 (human) ( 1 ) , Src (human) ( 1 )

References 

1

Li R, et al. (2017) Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins. J Biol Chem 292, 2830-2841
28073914   Curated Info