Lys32
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Home > Acetylation Site Page: > Lys32  -  ATRIP (human)

Site Information
GtGHPPskRARGFsA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 6217746

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , mass spectrometry ( 2 , 3 , 4 , 5 ) , modification-specific antibody ( 2 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on biological processes:
cell cycle regulation ( 2 ) , DNA repair, inhibited ( 2 )
Inhibit interaction with:
DNA ( 2 )

References 

1

Head PE, et al. (2017) Sirtuin 2 mutations in human cancers impair its function in genome maintenance. J Biol Chem 292, 9919-9931
28461331   Curated Info

2

Zhang H, et al. (2016) ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA. Cell Rep 14, 1435-47
26854234   Curated Info

3

Possemato A (2008) CST Curation Set: 5214; Year: 2008; Biosample/Treatment: cell line, HCT116/nicotinamide; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Antibodies Used to Purify Peptides prior to LCMS: Acetylated-Lysine (Ac-K2-100) Rabbit mAb Cat#: 9814, PTMScan(R) Acetyl-Lys Motif (Ac-K) Immunoaffinity Beads Cat#: 1989
Curated Info

4

Possemato A (2008) CST Curation Set: 5215; Year: 2008; Biosample/Treatment: cell line, HCT116/TSA; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Antibodies Used to Purify Peptides prior to LCMS: Acetylated-Lysine (Ac-K2-100) Rabbit mAb Cat#: 9814, PTMScan(R) Acetyl-Lys Motif (Ac-K) Immunoaffinity Beads Cat#: 1989
Curated Info

5

Possemato A (2008) CST Curation Set: 5211; Year: 2008; Biosample/Treatment: cell line, HCT116/nicotinamide; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Antibodies Used to Purify Peptides prior to LCMS: Acetylated-Lysine (Ac-K2-100) Rabbit mAb Cat#: 9814, PTMScan(R) Acetyl-Lys Motif (Ac-K) Immunoaffinity Beads Cat#: 1989
Curated Info