Tyr297

Site Information
RQQQDEAyLAsLRAD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 473454

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Relevant cell line - cell type - tissue:	HUES-9 ('stem, embryonic') ( 1 ) , Jurkat (T lymphocyte) ( 3 ) , MDA-MB-231 (breast cell) [Syk (human), transfection, Tet-reponsive Syk-inducible system] ( 2 )

References
1	Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3 21406692 Curated Info
2	Iliuk AB, et al. (2010) In-depth analyses of kinase-dependent tyrosine phosphoproteomes based on metal ion-functionalized soluble nanopolymers. Mol Cell Proteomics 9, 2162-72 20562096 Curated Info
3	Moritz A (2006) CST Curation Set: 1654; Year: 2006; Biosample/Treatment: cell line, Jurkat/pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info