Lys74
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Home > Sumoylation Site Page: > Lys74  -  CTCF (human)

Site Information
DPTLLQMkTEVMEGT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 6124703

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , alpha-TC6 (pancreatic) ( 1 ) , hTCEpi (epithelial) ( 1 )

Upstream Regulation
Regulatory protein:
SENP3 (human) ( 1 ) , SENP5 (human) ( 1 )
Treatments:
H2O2 ( 1 ) , heat_shock ( 1 ) , hyperosmotic shock ( 1 ) , hypoxia ( 1 ) , siRNA ( 1 ) , UV ( 1 )

Downstream Regulation
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Wang J, Wang Y, Lu L (2012) De-SUMOylation of CCCTC binding factor (CTCF) in hypoxic stress-induced human corneal epithelial cells. J Biol Chem 287, 12469-79
22354964   Curated Info

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