Tyr259
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Home > Phosphorylation Site Page: > Tyr259  -  RSK4 (mouse)

Site Information
sFCGtVEyMAPEVVN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 472958

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 )
Relevant cell line - cell type - tissue:
'fat, brown' ( 4 ) , embryo ( 2 ) , heart ( 4 ) , liver ( 1 , 4 ) , lung ( 4 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 3 ) , pancreas ( 4 ) , spleen ( 4 ) , testis ( 4 )

References 

1

Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83
23140645   Curated Info

2

Stokes MP, et al. (2012) PTMScan Direct: Identification and Quantification of Peptides from Critical Signaling Proteins by Immunoaffinity Enrichment Coupled with LC-MS/MS. Mol Cell Proteomics 11, 187-201
22322096   Curated Info

3

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info

4

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info