Ser383
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Home > Phosphorylation Site Page: > Ser383  -  HIF2A (human)

Site Information
SSGKGAVsEkSNFLF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 59087903

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
liver cancer ( 1 ) , hepatocellular carcinoma ( 1 )
Relevant cell line - cell type - tissue:
HepG2 (hepatic) ( 1 ) , Huh7 (hepatic) ( 1 )

Upstream Regulation
Kinases, in vitro:
CK1D (human) ( 1 )

Downstream Regulation
Effects of modification on HIF2A:
intracellular localization ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Pangou E, et al. (2016) HIF-2α phosphorylation by CK1δ promotes erythropoietin secretion in liver cancer cells under hypoxia. J Cell Sci 129, 4213-4226
27686097   Curated Info

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