Ser183
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.9
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser183  -  CASP9 (human)

Site Information
GLRTRTGsNIDCEkL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448528

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 2 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 2 )

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 2 )
Kinases, in vitro:
PKACA (human) ( 1 , 2 )
Treatments:
cAMP_analog ( 2 )

Downstream Regulation
Effects of modification on CASP9:
enzymatic activity, inhibited ( 1 , 2 ) , molecular association, regulation ( 2 ) , protein conformation ( 1 )
Inhibit interaction with:
APAF (human) ( 2 )

References 

1

Serrano BP, Hardy JA (2018) Phosphorylation by protein kinase A disassembles the caspase-9 core. Cell Death Differ
29352269   Curated Info

2

Martin MC, et al. (2005) Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c. J Biol Chem 280, 15449-55
15703181   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2024 Cell Signaling Technology, Inc.