Ser229
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser229  -  VEGFR2 (human)

Site Information
RIYDVVLsPSHGIEL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 56790201

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CDK5 (human) ( 1 )
Treatments:
seliciclib ( 1 )

Downstream Regulation
Effects of modification on VEGFR2:
receptor internalization, inhibited ( 1 )
Effects of modification on biological processes:
cell adhesion, altered ( 1 ) , cell motility, induced ( 1 )

References 

1

Xie W, et al. (2016) Phosphorylation of kinase insert domain receptor by cyclin-dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas. Oncotarget 7, 50883-50894
27438154   Curated Info