Lys89

Javascript is not enabled on this browser. This site will not work properly without Javascript.

Home > Ubiquitylation Site Page: > Lys89 - HMGCR (human)

Site Information
NLRQLGSkYILGIAG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 55607400

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	CHO-K1 (fibroblast) ( 1 )

Downstream Regulation
Effects of modification on HMGCR:	protein degradation ( 1 ) , ubiquitination ( 1 )

References
1	Jiang SY, et al. (2019) Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase. PLoS Genet 15, e1008289 31323021 Curated Info

Developed with grants from

and literature mining with Linguamatics

PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.