Ser25
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Home > Phosphorylation Site Page: > Ser25  -  MOS (mouse)

Site Information
SVDSRSCsIPLVAPR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448659

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 2 ) , [32P] bio-synthetic labeling ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 , 2 ) , phosphopeptide mapping ( 1 , 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKACA (mouse) ( 2 )
Kinases, in vitro:
MOS (mouse) ( 2 ) , PKACA (mouse) ( 2 )
Treatments:
cAMP_analog ( 2 ) , colforsin ( 2 )

Downstream Regulation
Effects of modification on MOS:
enzymatic activity, inhibited ( 1 )

References 

1

Yang Y, et al. (1998) Evidence of a functional interaction between serine 3 and serine 25 Mos phosphorylation sites. A dominant inhibitory role of serine 25 phosphorylation on Mos protein kinase. J Biol Chem 273, 15946-53
9632642   Curated Info

2

Yang Y, Herrmann CH, Arlinghaus RB, Singh B (1996) Inhibition of v-Mos kinase activity by protein kinase A. Mol Cell Biol 16, 800-9
8622681   Curated Info