Thr790
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Home > Phosphorylation Site Page: > Thr790  -  CDH1 (human)

Site Information
TRNDVAPtLMsVPRy   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 55578700

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
CHO (fibroblast) ( 1 ) , MDCK (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCD (human) ( 1 )
Kinases, in vitro:
PKCD (human) ( 1 )

Downstream Regulation
Effects of modification on CDH1:
activity, inhibited ( 1 ) , molecular association, regulation ( 1 )
Inhibit interaction with:
CBLL1 (human) ( 1 ) , CTNNB1 (human) ( 1 )

References 

1

Chen CL, et al. (2016) Phosphorylation of E-cadherin at threonine 790 by protein kinase Cδ reduces β-catenin binding and suppresses the function of E-cadherin. Oncotarget 7, 37260-37276
27203386   Curated Info

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