Thr156

Site Information
SQITSQVtGQIGWRR SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 448782

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:	HeLa (cervical) [AP2M1 (rat)] ( 2 )

Downstream Regulation
Effects of modification on AP2M1:	intracellular localization ( 2 ) , molecular association, regulation ( 1 ) , protein conformation ( 1 )
Induce interaction with:	TGOLN2 (human) ( 1 )

References
1	Höning S, et al. (2005) Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2. Mol Cell 18, 519-31 15916959 Curated Info
2	Olusanya O, Andrews PD, Swedlow JR, Smythe E (2001) Phosphorylation of threonine 156 of the mu2 subunit of the AP2 complex is essential for endocytosis in vitro and in vivo. Curr Biol 11, 896-900 11516654 Curated Info