Thr100
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Home > Phosphorylation Site Page: > Thr100  -  RHOA (human)

Site Information
ENIPEKWtPEVkHFC   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 53332704

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
ERK1 (human) ( 1 )
Kinases, in vitro:
ERK1 (human) ( 1 )
Treatments:
EGF ( 1 ) , U0126 ( 1 )

Downstream Regulation
Effects of modification on RHOA:
activity, induced ( 1 ) , intracellular localization ( 1 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )
Induce interaction with:
ROCK1 (human) ( 1 )

References 

1

Tong J, Li L, Ballermann B, Wang Z (2016) Phosphorylation and Activation of RhoA by ERK in Response to Epidermal Growth Factor Stimulation. PLoS One 11, e0147103
26816343   Curated Info