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Site Information |
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DIkILIAsPsPTHIH SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 470105 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Downstream Regulation | |
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Effects of modification on HIF1A: | |
Effects of modification on biological processes: | |
Induce interaction with: | |
Inhibit interaction with: |
References | |
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Yfantis A, Mylonis I, Simos G (2023) Direct interaction between mortalin and HIF-1α at the mitochondria inhibits apoptosis by blocking recruitment of Bax. FEBS J
36825991 Curated Info |
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Han HJ, et al. (2016) Peptidyl Prolyl Isomerase PIN1 Directly Binds to and Stabilizes Hypoxia-Inducible Factor-1α. PLoS One 11, e0147038
26784107 Curated Info |
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Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151 Curated Info |
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Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546 Curated Info |
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Mylonis I, Chachami G, Paraskeva E, Simos G (2008) Atypical CRM1-dependent nuclear export signal mediates regulation of hypoxia-inducible factor-1alpha by MAPK. J Biol Chem 283, 27620-7
18687685 Curated Info |
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Mylonis I, et al. (2006) Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha. J Biol Chem 281, 33095-106
16954218 Curated Info |