Lys22
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Ubiquitylation Site Page: > Lys22  -  Bcl-2 (human)

Site Information
VMKYIHYkLSQRGYE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 52477000

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
PPAR-alpha (human) ( 2 )

Downstream Regulation
Effects of modification on Bcl-2:
protein degradation ( 2 )
Effects of modification on biological processes:
apoptosis, induced ( 2 )

References 

1

Boeing S, et al. (2016) Multiomic Analysis of the UV-Induced DNA Damage Response. Cell Rep 15, 1597-1610
27184836   Curated Info

2

Gao J, et al. (2015) PPARĪ± induces cell apoptosis by destructing Bcl2. Oncotarget 6, 44635-42
26556865   Curated Info