Ser440

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Home > Phosphorylation Site Page: > Ser440 - CD4 (human)

Site Information
sQIkRLLsEKKTCQC SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 469618

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	Jurkat (T lymphocyte) ( 1 )

Upstream Regulation
Putative in vivo kinases:	PKCA (human) ( 1 )
Treatments:	bisindolylmaleimide ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on CD4:	intracellular localization ( 1 )

References
1	Jin YJ, Zhang X, Boursiquot JG, Burakoff SJ (2004) CD4 phosphorylation partially reverses Nef down-regulation of CD4. J Immunol 173, 5495-500 15494497 Curated Info

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