Ser149
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Home > O-GlcNAc Site Page: > Ser149  -  p53 (human)

Site Information
PVQLWVDsTPPPGTR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 5148303

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
breast cancer ( 1 ) , lung cancer ( 1 ) , non-small cell lung cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
streptozotocin ( 1 )

Downstream Regulation
Effects of modification on p53:
phosphorylation ( 1 ) , protein stabilization ( 1 ) , ubiquitination ( 1 )

References 

1

Yang WH, et al. (2006) Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability. Nat Cell Biol 8, 1074-83
16964247   Curated Info