Lys125
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Home > Ubiquitylation Site Page: > Lys125  -  CARD9 (human)

Site Information
LLMTEVMkLQKKVQD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 50760800

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
leukemia ( 1 ) , acute myelogenous leukemia ( 1 )
Relevant cell line - cell type - tissue:
dendritic cell ( 1 ) , HEK293T (epithelial) ( 1 ) , macrophage-bone marrow ( 1 ) , THP1 (myeloid) ( 1 )

Downstream Regulation
Effects of modification on CARD9:
activity, induced ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 ) , transcription, induced ( 1 )

References 

1

Cao Z, et al. (2015) Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation. Immunity 43, 715-26
26488816   Curated Info