Ser71

Site Information
GDDDGQRsRSSSSAQ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 50440900

In vivo Characterization
Methods used to characterize site in vivo:	flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	3T3 (fibroblast) ( 1 ) , HEK293T (epithelial) ( 1 ) , MEF (fibroblast) ( 1 )

Downstream Regulation
Effects of modification on p16-INK4A iso3:	molecular association, regulation ( 1 ) , protein degradation ( 1 ) , ubiquitination ( 1 )
Induce interaction with:	FBW1B (human) ( 1 )

References
1	Nakagawa T, et al. (2015) S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation. Mol Cell Biol 35, 3517-27 26240281 Curated Info