Ser71
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Home > Phosphorylation Site Page: > Ser71  -  p16-INK4A iso3 (mouse)

Site Information
GDDDGQRsRSSSSAQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 50440900

In vivo Characterization
Methods used to characterize site in vivo:
flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
3T3 (fibroblast) ( 1 ) , HEK293T (epithelial) ( 1 ) , MEF (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
p70S6K (mouse) ( 1 )
Kinases, in vitro:
p70S6K (mouse) ( 1 )
Treatments:
serum ( 1 )

Downstream Regulation
Effects of modification on p16-INK4A iso3:
molecular association, regulation ( 1 ) , protein degradation ( 1 ) , ubiquitination ( 1 )
Induce interaction with:
FBW1B (human) ( 1 )

References 

1

Nakagawa T, et al. (2015) S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation. Mol Cell Biol 35, 3517-27
26240281   Curated Info