Thr231
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Home > Phosphorylation Site Page: > Thr231  -  Elf-1 (human)

Site Information
CPkYIkWtQREKGIF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4825111

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
SLE ( 1 )
Relevant cell line - cell type - tissue:
Jurkat (T lymphocyte) ( 1 ) , T lymphocyte-blood ( 1 )

Upstream Regulation
Putative upstream phosphatases:
PPP2CA (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
transcription, altered ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
SLE ( 1 )

References 

1

Juang YT, et al. (2008) PP2A dephosphorylates Elf-1 and determines the expression of CD3zeta and FcRgamma in human systemic lupus erythematosus T cells. J Immunol 181, 3658-64
18714041   Curated Info