Tyr1208
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Home > Phosphorylation Site Page: > Tyr1208  -  HER4 (human)

Site Information
EyVNEPLyLNTFANT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4825109

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on HER4:
molecular association, regulation ( 3 )
Induce interaction with:
GRB2 (human) ( 3 )

References 

1

Moritz A (2010) CST Curation Set: 9059; Year: 2010; Biosample/Treatment: cell line, HeLa/Peroxide; Disease: cervical adenocarcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

2

Kaushansky A, et al. (2008) System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties. Chem Biol 15, 808-17
18721752   Curated Info

3

Schulze WX, Deng L, Mann M (2005) Phosphotyrosine interactome of the ErbB-receptor kinase family. Mol Syst Biol 1, 2005.0008
16729043   Curated Info