Thr15
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Home > Phosphorylation Site Page: > Thr15  -  CHIP (mouse)

Site Information
EGGARLGtGGGGsPD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4786029

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 )
Disease tissue studied:
neuroblastoma ( 6 )
Relevant cell line - cell type - tissue:
'fat, brown' ( 8 ) , brain ( 8 , 9 ) , heart ( 8 ) , kidney ( 8 ) , liver ( 8 ) , lung ( 8 ) , macrophage-peritoneum ( 3 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 5 ) , mpkCCD (renal) ( 10 ) , N1E-115 (neuron) ( 6 ) , neuron:postsynaptic density-'brain, hippocampus, CA1 region' ( 1 ) , pancreas ( 8 ) , PC-12 (chromaffin) [TrkA (rat), transfection] ( 4 ) , PC-12 (chromaffin) ( 4 ) , RAW 264.7 (macrophage) ( 2 ) , spleen ( 8 ) , T lymphocyte-spleen ( 7 ) , testis ( 8 )

Upstream Regulation
Treatments:
long-term_potentiation ( 1 ) , LPA ( 6 )

References 

1

Li J, et al. (2016) Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome. Sci Signal 9, rs8
27507650   Curated Info

2

Pinto SM, et al. (2015) Quantitative phosphoproteomic analysis of IL-33-mediated signaling. Proteomics 15, 532-44
25367039   Curated Info

3

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

4

Biarc J, Chalkley RJ, Burlingame AL, Bradshaw RA (2012) The induction of serine/threonine protein phosphorylations by a PDGFR/TrkA chimera in stably transfected PC12 cells. Mol Cell Proteomics 11, 15-30
22027198   Curated Info

5

Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info

6

Wang Y, et al. (2011) Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction. J Biol Chem 286, 18190-201
21454597   Curated Info

7

Navarro MN, et al. (2011) Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes. Nat Immunol 12, 352-61
21399638   Curated Info

8

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

9

Wiƛniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
20415495   Curated Info

10

Rinschen MM, et al. (2010) Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor-dependent signaling pathways in renal collecting duct cells. Proc Natl Acad Sci U S A 107, 3882-7
20139300   Curated Info