Tyr1252
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Home > Phosphorylation Site Page: > Tyr1252  -  NMDAR2B (mouse)

Site Information
CKKAGNLyDIsEDNs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448165
Associated spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 ) , phosphopeptide mapping ( 3 )
Relevant cell line - cell type - tissue:
'brain, hippocampus' [Fyn (mouse)] ( 3 ) , brain ( 1 ) , HEK293T (epithelial) [Fyn (mouse)] ( 3 ) , HEK293T (epithelial) ( 2 )

Upstream Regulation
Putative in vivo kinases:
Fyn (mouse) ( 3 )
Treatments:
ephrin_B2 ( 2 )

References 

1

Guo A (2007) CST Curation Set: 2675; Year: 2007; Biosample/Treatment: tissue, brain/LY; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

2

Takasu MA, Dalva MB, Zigmond RE, Greenberg ME (2002) Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors. Science 295, 491-5
11799243   Curated Info

3

Nakazawa T, et al. (2001) Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor. J Biol Chem 276, 693-9
11024032   Curated Info