Ser339

Site Information
RAAsPPAsAsDLIEQ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 4755894

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 4 )
Disease tissue studied:	lung cancer ( 2 ) , non-small cell lung adenocarcinoma ( 2 ) , neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:	CLB-Bar ( 1 ) , HeLa (cervical) ( 4 ) , lung ( 2 )

References
1	Borenäs M, et al. (2024) ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition. Proc Natl Acad Sci U S A 121, e2315242121 38154064 Curated Info
2	Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96 23911959 Curated Info
3	Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25 22424773 Curated Info
4	Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5 21712546 Curated Info