Ser620
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Home > Phosphorylation Site Page: > Ser620  -  DVL2 (mouse)

Site Information
EsksGsGsESELSSR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4728125

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 2 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 3 )

Upstream Regulation
Treatments:
insulin ( 2 )

References 

1

Sacco F, et al. (2016) Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. Nat Commun 7, 13250
27841257   Curated Info

2

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

3

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info