Ser247
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Home > Phosphorylation Site Page: > Ser247  -  HNF1A (human)

Site Information
ECIQRGVsPsQAQGL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4704539

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
liver cancer ( 1 ) , hepatocellular carcinoma, surrounding tissue ( 3 )
Relevant cell line - cell type - tissue:
hepatocyte-liver ( 3 ) , HepG2 (hepatic) ( 1 ) , liver ( 2 )

References 

1

Zhao L, et al. (2014) Serine 249 phosphorylation by ATM protein kinase regulates hepatocyte nuclear factor-1α transactivation. Biochim Biophys Acta 1839, 604-20
24821553   Curated Info

2

Bian Y, et al. (2014) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics 96, 253-62
24275569   Curated Info

3

Han G, et al. (2010) Phosphoproteome analysis of human liver tissue by long-gradient nanoflow LC coupled with multiple stage MS analysis. Electrophoresis 31, 1080-9
20166139   Curated Info