Ser419

Site Information
APQRAQIssPNLRTR SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 4700959

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Relevant cell line - cell type - tissue:	'3T3-L1, differentiated' (adipocyte) ( 1 ) , 'fat, brown' ( 3 ) , kidney ( 3 ) , liver ( 3 ) , lung ( 3 ) , MEF (fibroblast) ( 2 ) , pancreas ( 3 ) , spleen ( 3 )

Upstream Regulation
Treatments:	insulin ( 1 ) , LY294002 ( 1 )

References
1	Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20 23684622 Curated Info
2	Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51 22942356 Curated Info
3	Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89 21183079 Curated Info