Ser320

Site Information
sstRRGGsLGQTARS SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 4700741

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 , 3 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	HER2 positive breast cancer ( 2 ) , luminal A breast cancer ( 2 ) , luminal B breast cancer ( 2 ) , breast cancer, triple negative ( 2 ) , leukemia ( 1 )
Relevant cell line - cell type - tissue:	BaF3 ('B lymphocyte, precursor') ( 1 ) , breast ( 2 ) , CHO-K1 (fibroblast) ( 1 ) , HeLa (cervical) ( 1 ) , HL60 (myeloid) ( 1 ) , liver ( 3 ) , RBL-2H3 (basophil) ( 1 )

Downstream Regulation
Effects of modification on LTB4R:	phosphorylation ( 1 )
Effects of modification on biological processes:	signaling pathway regulation ( 1 )

References
1	Nakanishi Y, et al. (2018) Stepwise phosphorylation of leukotriene B receptor 1 defines cellular responses to leukotriene B. Sci Signal 11 30131369 Curated Info
2	Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62 27251275 Curated Info
3	Bian Y, et al. (2014) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics 96, 253-62 24275569 Curated Info
4	Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21 23312004 Curated Info