Ser26
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.4
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser26  -  RRAD (mouse)

Site Information
ERDRRrGstPWGPAP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4700219

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 2 , 3 ) , C2C12 (myoblast) ( 6 ) , heart ( 5 ) , HEK293T (epithelial) ( 1 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 4 ) , spleen ( 5 )

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )
Treatments:
insulin ( 3 ) , NKH_477 ( 1 )

Downstream Regulation
Effects of modification on RRAD:
activity, induced ( 1 ) , molecular association, regulation ( 1 )
Inhibit interaction with:
CACNA1C (human) ( 1 )

References 

1

Liu G, et al. (2020) Mechanism of adrenergic Ca1.2 stimulation revealed by proximity proteomics. Nature 577, 695-700
31969708   Curated Info

2

Parker BL, et al. (2015) Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Sci Signal 8, rs6
26060331   Curated Info

3

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

4

Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info

5

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

6

Possemato A (2008) CST Curation Set: 5031; Year: 2008; Biosample/Treatment: cell line, C2C12/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info