Thr66
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Home > Phosphorylation Site Page: > Thr66  -  IRAK1 (mouse)

Site Information
CERSEQRtASVLWPW   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447722

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
adrenal cancer ( 1 ) , pheochromocytoma ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , PC-12 (chromaffin) ( 1 )

Upstream Regulation
Kinases, in vitro:
PKCI (human) ( 1 )

Downstream Regulation
Effects of modification on IRAK1:
enzymatic activity, induced ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )
Induce interaction with:
PKCI (human) ( 1 )

References 

1

Mamidipudi V, Lin C, Seibenhener ML, Wooten MW (2004) Regulation of interleukin receptor-associated kinase (IRAK) phosphorylation and signaling by iota protein kinase C. J Biol Chem 279, 4161-5
14684752   Curated Info

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