|
Powered by Cell Signaling Technology |
Site Information |
---|
TIRMSFVkGWGAEYR SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 466353 |
In vivo Characterization | |
---|---|
Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
---|---|
Treatments: |
Downstream Regulation | |
---|---|
Effects of modification on SMAD3: | |
Effects of modification on biological processes: |
References | |
---|---|
Zhong X, et al. (2020) SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells. Cell Mol Gastroenterol Hepatol 10, 341-364
32305562 Curated Info |
|
Weinert BT, et al. (2013) Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell Rep 4, 842-51
23954790 Curated Info |
|
Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7
23749302 Curated Info |
|
Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25
22424773 Curated Info |
|
Choudhary C, et al. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-40
19608861 Curated Info |
|
Inoue Y, et al. (2007) Smad3 is acetylated by p300/CBP to regulate its transactivation activity. Oncogene 26, 500-8
16862174 Curated Info |