Ser252
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Home > Phosphorylation Site Page: > Ser252  -  Myc (human)

Site Information
PPTTssDsEEEQEDE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 466014

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 1 ) , phosphopeptide mapping ( 2 )
Disease tissue studied:
prostate cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CK1A (human) ( 1 )
Kinases, in vitro:
CK2A1 (human) ( 2 )

Downstream Regulation
Effects of modification on Myc:
protein degradation ( 1 ) , ubiquitination ( 1 )

References 

1

Li L, et al. (2011) GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction. Cancer Res 71, 7694-704
22025562   Curated Info

2

L├╝scher B, Kuenzel EA, Krebs EG, Eisenman RN (1989) Myc oncoproteins are phosphorylated by casein kinase II. EMBO J 8, 1111-9
2663470   Curated Info