Thr275
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Home > Phosphorylation Site Page: > Thr275  -  GSK3B (human)

Site Information
AMBIGUOUS SITES: ognl.NoConversionPossible:
EIIKVLGtPtREQIR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4271311

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 )
Relevant cell line - cell type - tissue:
HCT116 (intestinal) ( 3 ) , HeLa S3 (cervical) ( 4 ) , HeLa_Meta (cervical) ( 2 ) , HeLa_Pro (cervical) ( 2 ) , HeLa_Telo (cervical) ( 2 ) , K562 (erythroid) ( 1 ) , MV4-11 (macrophage) ( 3 )

Upstream Regulation
Treatments:
nocodazole ( 4 ) , thymidine ( 4 )

References 

1

Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71
23186163   Curated Info

2

Dulla K, et al. (2010) Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Mol Cell Proteomics 9, 1167-81
20097925   Curated Info

3

Oppermann FS, et al. (2009) Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics 8, 1751-64
19369195   Curated Info

4

Daub H, et al. (2008) Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell 31, 438-48
18691976   Curated Info