Ser975

Site Information
LPAPtSTsPSRGNSR SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 4169437

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 )
Disease tissue studied:	pancreatic ductal adenocarcinoma ( 1 )
Relevant cell line - cell type - tissue:	'pancreatic, ductal'-pancreas ( 1 ) , 293 (epithelial) [AT1 (human), transfection] ( 2 ) , HeLa (cervical) ( 3 , 4 )

Upstream Regulation
Treatments:	EGF ( 4 )

References
1	Britton D, et al. (2014) Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets. PLoS One 9, e90948 24670416 Curated Info
2	Xiao K, et al. (2010) Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proc Natl Acad Sci U S A 107, 15299-304 20686112 Curated Info
3	Chen RQ, et al. (2009) CDC25B mediates rapamycin-induced oncogenic responses in cancer cells. Cancer Res 69, 2663-8 19276368 Curated Info
4	Cantin GT, et al. (2008) Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. J Proteome Res 7, 1346-51 18220336 Curated Info