Ser170
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Home > Phosphorylation Site Page: > Ser170  -  ataxin-7L3 iso2 (human)

Site Information
LPFQNPNsPRRSKSL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 41450537

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 )
Disease tissue studied:
HER2 positive breast cancer ( 1 ) , luminal A breast cancer ( 1 ) , luminal B breast cancer ( 1 ) , breast cancer, triple negative ( 1 ) , lung cancer ( 4 ) , non-small cell lung cancer ( 4 ) , melanoma skin cancer ( 2 )
Relevant cell line - cell type - tissue:
breast ( 1 ) , H2077 (pulmonary) ( 4 ) , H322 (pulmonary) ( 4 ) , H322M (pulmonary) ( 4 ) , HOP62 (pulmonary) ( 4 ) , Jurkat (T lymphocyte) ( 3 ) , NCI-H520 (squamous) ( 4 ) , PC9 (pulmonary) ( 4 ) , WM239A (epidermal) ( 2 )

References 

1

Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275   Curated Info

2

Stuart SA, et al. (2015) A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells. Mol Cell Proteomics 14, 1599-615
25850435   Curated Info

3

Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7
23749302   Curated Info

4

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info