Tyr705
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Home > Phosphorylation Site Page: > Tyr705  -  TrkC (human)

Site Information
FGMsRDVySTDyyRL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 464876

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 3 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 3 ) , phospho-antibody ( 3 ) , western blotting ( 3 )
Disease tissue studied:
leukemia ( 1 , 2 ) , acute myelogenous leukemia ( 1 , 2 )
Relevant cell line - cell type - tissue:
3T3 (fibroblast) ( 3 ) , MO-91 (myeloid) ( 1 , 2 )

Downstream Regulation
Effects of modification on biological processes:
carcinogenesis, induced ( 3 ) , cell growth, induced ( 3 ) , signaling pathway regulation ( 3 )

References 

1

Gu T (2006) CST Curation Set: 1174; Year: 2006; Biosample/Treatment: cell line, MO-91/-; Disease: acute myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

2

Gu T (2006) CST Curation Set: 1175; Year: 2006; Biosample/Treatment: cell line, MO-91/-; Disease: acute myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

Wai DH, et al. (2000) The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells. Oncogene 19, 906-15
10702799   Curated Info