Tyr454

Site Information
VICAEEPyICkDFPE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 464797
Associated spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Disease tissue studied:	leukemia ( 2 ) , acute myelogenous leukemia ( 2 ) , lymphoma ( 3 ) , anaplastic large cell lymphoma ( 3 )
Relevant cell line - cell type - tissue:	MKPL-1 (megakaryoblast) ( 1 , 2 ) , TS (lymphocyte) ( 3 )

References
1	Gu TL, et al. (2007) A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia. Blood 110, 323-33 17360941 Curated Info
2	Gu T (2006) CST Curation Set: 1557; Year: 2006; Biosample/Treatment: cell line, MKPL-1/untreated; Disease: acute myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info
3	Goss V (2006) CST Curation Set: 1305; Year: 2006; Biosample/Treatment: cell line, TS/A2; Disease: anaplastic large cell lymphoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info