Thr395

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Home > Phosphorylation Site Page: > Thr395 - NRF2 (human)

Site Information
VKQNGPKtPVHSSGD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 40642203

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	astrocyte ( 1 )

Upstream Regulation
Kinases, in vitro:	CDK5 (human) ( 1 )

Downstream Regulation
Effects of modification on NRF2:	intracellular localization ( 1 )

References
1	Jimenez-Blasco D, et al. (2015) Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway. Cell Death Differ 22, 1877-89 25909891 Curated Info

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