Thr421
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Home > Phosphorylation Site Page: > Thr421  -  p70S6K iso2 (human)

Site Information
RFIGsPRtPVsPVKF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448358

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 , 3 ) , western blotting ( 3 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
EGF ( 3 )

References 

1

Tan X, et al. (2016) Phosphoproteome Analysis of Invasion and Metastasis-Related Factors in Pancreatic Cancer Cells. PLoS One 11, e0152280
27014871   Curated Info

2

Hong S, et al. (2014) Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation. J Biol Chem 289, 13132-41
24652283   Curated Info

3

Tumurkhuu M, et al. (2013) A novel SOS1 mutation in Costello/CFC syndrome affects signaling in both RAS and PI3K pathways. J Recept Signal Transduct Res 33, 124-8
23528009   Curated Info