Thr581
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Home > Phosphorylation Site Page: > Thr581  -  RSK4 (human)

Site Information
GENGLLLtPCYTANF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4045800

In vivo Characterization
Methods used to characterize site in vivo:
peptide sequencing ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
CHO (fibroblast) ( 1 ) , COS (fibroblast) ( 1 ) , ES (stem) ( 1 )

Upstream Regulation
Treatments:
EGF ( 1 ) , insulin ( 1 ) , U0126 ( 1 )

Downstream Regulation
Effects of modification on RSK4:
enzymatic activity, induced ( 1 ) , phosphorylation ( 1 )

References 

1

D├╝mmler BA, et al. (2005) Functional characterization of human RSK4, a new 90-kDa ribosomal S6 kinase, reveals constitutive activation in most cell types. J Biol Chem 280, 13304-14
15632195   Curated Info