Lys433

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Home > Ubiquitylation Site Page: > Lys433 - PINK1 (human)

Site Information
RAVIDYSkADAWAVG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 40212809

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , western blotting ( 1 )
Disease tissue studied:	neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:	SH-SY5Y (neural crest) ( 1 )

Upstream Regulation
Regulatory protein:	SARM1 (human) ( 1 )

Downstream Regulation
Effects of modification on PINK1:	molecular association, regulation ( 1 ) , protein stabilization ( 1 )
Induce interaction with:	TOM20 (human) ( 1 )

References
1	Murata H, Sakaguchi M, Kataoka K, Huh NH (2013) SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol Biol Cell 24, 2772-84 23885119 Curated Info

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