Tyr299

Site Information
HKLGGGQyGEVyVGV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 3973063
Associated spectra: 2 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , phosphopeptide mapping ( 1 )
Disease tissue studied:	leukemia ( 2 ) , chronic myelogenous leukemia ( 2 )
Relevant cell line - cell type - tissue:	K562 (erythroid) ( 2 ) , SF9 ( 1 )

Upstream Regulation
Kinases, in vitro:	PDGFRB (human) ( 1 )

References
1	Wu K, et al. (2021) Platelet-derived growth factor receptor beta activates Abl2 via direct binding and phosphorylation. J Biol Chem 297, 100883 34144039 Curated Info
2	Moritz A (2007) CST Curation Set: 2779; Year: 2007; Biosample/Treatment: cell line, K562/-; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info

References

Wu K, et al. (2021) Platelet-derived growth factor receptor beta activates Abl2 via direct binding and phosphorylation. J Biol Chem 297, 100883
34144039 Curated Info

Moritz A (2007) CST Curation Set: 2779; Year: 2007; Biosample/Treatment: cell line, K562/-; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info