Ser495
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Home > Phosphorylation Site Page: > Ser495  -  PINK1 (human)

Site Information
ALLQREAsKRPSARV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 396518801

In vivo Characterization
Methods used to characterize site in vivo:
flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
heart ( 1 ) , myocyte-heart ( 1 )

Upstream Regulation
Putative in vivo kinases:
AMPKA2 (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
autophagy, induced ( 1 )

References 

1

Wang B, et al. (2017) AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation. Circ Res
29284690   Curated Info