Tyr579

Site Information
IPECADKyyDALVkA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 463506
Associated spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 )
Disease tissue studied:	leukemia ( 3 , 4 ) , acute lymphocytic leukemia ( 3 ) , acute myelogenous leukemia ( 4 ) , liver cancer ( 1 , 2 ) , cholangiocellular carcinoma ( 1 ) , hepatocellular carcinoma ( 2 )
Relevant cell line - cell type - tissue:	CTV-1 (myeloid) ( 4 ) , DU.528 ('stem, hematopoietic') ( 3 ) , hepatocyte-liver ( 2 ) , liver ( 1 )

References
1	Gu TL, et al. (2011) Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma. PLoS One 6, e15640 21253578 Curated Info
2	Gu T (2009) CST Curation Set: 7522; Year: 2009; Biosample/Treatment: liver, hepatocyte/untreated; Disease: liver cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info
3	Gu T (2006) CST Curation Set: 1789; Year: 2006; Biosample/Treatment: cell line, DU.528/untreated; Disease: acute lymphocytic leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info
4	Goss V (2004) CST Curation Set: 404; Year: 2004; Biosample/Treatment: cell line, CTV-1/-; Disease: acute myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info