Tyr163
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Home > Phosphorylation Site Page: > Tyr163  -  Kv1.3 (human)

Site Information
FDAILyyyQSGGRIR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3820936

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 )

Upstream Regulation
Regulatory protein:
GRB10 (human) ( 1 )
Putative in vivo kinases:
TrkB (human) ( 1 )
Treatments:
BDNF ( 1 )

Downstream Regulation
Effects of modification on Kv1.3:
activity, inhibited ( 1 )

References 

1

Colley BS, et al. (2009) Brain-derived neurotrophic factor modulation of Kv1.3 channel is disregulated by adaptor proteins Grb10 and nShc. BMC Neurosci 10, 8
19166614   Curated Info

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