Tyr590
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Home > Phosphorylation Site Page: > Tyr590  -  GluR6 (human)

Site Information
RFSPYEWyNPHPCNP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 36320701

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 1 )

Downstream Regulation
Effects of modification on GluR6:
activity, induced ( 1 ) , protein conformation ( 1 ) , receptor internalization, induced ( 1 )
Effects of modification on biological processes:
endocytosis, induced ( 1 )

References 

1

Zhu QJ, et al. (2014) Tyrosine phosphorylation of GluK2 up-regulates kainate receptor-mediated responses and downstream signaling after brain ischemia. Proc Natl Acad Sci U S A 111, 13990-5
25201974   Curated Info