Lys981
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Home > Acetylation Site Page: > Lys981  -  p300 (human)

Site Information
QEVkMEAkMEVDQPE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 461473

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 3 , 4 )
Relevant cell line - cell type - tissue:
HCT116 (intestinal) ( 3 , 4 ) , MV4-11 (macrophage) ( 1 )

Upstream Regulation
Treatments:
vorinostat ( 1 )

References 

1

Choudhary C, et al. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-40
19608861   Curated Info

2

Black JC, et al. (2008) The SIRT2 deacetylase regulates autoacetylation of p300. Mol Cell 32, 449-55
18995842   Curated Info

3

Li Y (2005) CST Curation Set: 966; Year: 2005; Biosample/Treatment: cell line, HCT116/serum starved; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Antibodies Used to Purify Peptides prior to LCMS: Acetylated-Lysine Antibody Cat#: 9441
Curated Info

4

Li Y (2005) CST Curation Set: 967; Year: 2005; Biosample/Treatment: cell line, HCT116/EGF; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Antibodies Used to Purify Peptides prior to LCMS: Acetylated-Lysine Antibody Cat#: 9441
Curated Info