Tyr352
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Home > Phosphorylation Site Page: > Tyr352  -  NKAP (human)

Site Information
ASFECSGyVMsGsRH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 34731681

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 2 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
erythrocyte-blood ( 1 ) , HEK293T (epithelial) ( 1 ) , Jurkat (T lymphocyte) ( 2 ) , MEF (fibroblast) ( 1 )

Downstream Regulation
Effects of modification on NKAP:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )
Induce interaction with:
HDAC3 (human) ( 1 )

References 

1

Shapiro MJ, et al. (2019) NKAP Must Associate with HDAC3 to Regulate Hematopoietic Stem Cell Maintenance and Survival. J Immunol
30804042   Curated Info

2

Zhou J (2012) CST Curation Set: 14432; Year: 2012; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info