Tyr1128
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Home > Phosphorylation Site Page: > Tyr1128  -  HER4 (human)

Site Information
EDSSTQRySADPTVF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 461025

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 )
Disease tissue studied:
lung cancer ( 2 ) , non-small cell lung cancer ( 2 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , lung ( 2 )

Downstream Regulation
Effects of modification on HER4:
molecular association, regulation ( 1 )
Induce interaction with:
STAT1 (human) ( 1 ) , Src (human) ( 1 )

References 

1

Kaushansky A, et al. (2008) System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties. Chem Biol 15, 808-17
18721752   Curated Info

2

Guo A (2006) CST Curation Set: 1429; Year: 2006; Biosample/Treatment: tissue, lung/-; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info