Thr491
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Home > Phosphorylation Site Page: > Thr491  -  STK33 (human)

Site Information
EMEKTPVtPsQGtAT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 460956

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 , 5 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 2 ) , HeLa (cervical) ( 3 ) , HeLa_Meta (cervical) ( 1 ) , HeLa_Pro (cervical) ( 1 ) , HeLa_Telo (cervical) ( 1 ) , M059K (glial) ( 4 , 5 )

Upstream Regulation
Treatments:
MG132 ( 1 ) , MG132_withdrawal ( 1 )

References 

1

Dulla K, et al. (2010) Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Mol Cell Proteomics 9, 1167-81
20097925   Curated Info

2

Gauci S, et al. (2009) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal Chem 81, 4493-501
19413330   Curated Info

3

Zhou J (2009) CST Curation Set: 6247; Year: 2009; Biosample/Treatment: cell line, HeLa/UV; Disease: cervical adenocarcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho(Ser/Thr) ATM/ATR Substrate Antibody (polyAB) Cat#: 3005, PTMScan(R) Phospho-ATM/ATR Substrate Motif (pS/pTQ) Immunoaffinity Beads Cat#: 1980
Curated Info

4

Stokes M (2006) CST Curation Set: 1482; Year: 2006; Biosample/Treatment: cell line, M059K/untreated; Disease: glioblastoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS:p[ST]
Curated Info

5

Stokes M (2005) CST Curation Set: 1063; Year: 2005; Biosample1/Treatment/Isotope: cell line, M059K/none/L, Biosample2/Treatment/Isotope: cell line, M059K/UV/H; Disease: glioblastoma; SILAC: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) ATM/ATR Substrate Antibody Cat#: 2851
Curated Info